A small biotech company preparing for a pivotal Phase 3 trial in a challenging CNS indication had selected a CRO with deep therapeutic insight but limited experience in complex global delivery. The sponsor’s internal team was lean, with functional gaps in oversight, vendor coordination, and contract governance. When COVID-19 introduced added risk, the need for hands-on support became urgent. Seuss+ was brought in first to review a contract—then rapidly engaged to deliver fully integrated support across the trial lifecycle.